Members' NAVLE study guide

Feline Hyperthyroidism

1,546 words 7 min read Reviewed November 14, 2026

Hyperthyroidism is the most common feline endocrine disease of mature and senior cats. Autonomous thyroid tissue makes too much thyroxine (T4) and triiodothyronine (T3), which raises metabolic rate and strains the heart, gut and kidneys. The exam often combines it with chronic kidney disease (CKD), because treating the thyroid can reveal hidden kidney disease.

Key facts

Hyperthyroidism at a glance
  • Species and system: cat, endocrine; affects cardiovascular, renal and GI systems.
  • Cause: functional thyroid adenoma or adenomatous hyperplasia; both lobes are affected in about 70% of cats. Carcinoma accounts for under 3% of cases.
  • Signalment: most common in cats over 7 years old.
  • Classic presentation: weight loss despite a voracious appetite, hyperactivity, tachycardia and a palpable thyroid nodule.
  • Zoonotic or reportable: no.

What's inside

13 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Hyperthyroidism and kidney disease
  7. Treatment and management
  8. Don't confuse hyperthyroidism with
  9. Prognosis
  10. Working through a case
  11. Quick review
  12. Test yourself
  13. References
The full guide also has 4 tables, 3 self-test questions and 6 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

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