Members' NAVLE study guide

Feline Hyperparathyroidism

1,594 words 8 min read Reviewed November 14, 2026

Hyperparathyroidism means too much parathyroid hormone (PTH) is being released, which disturbs calcium and phosphorus balance. In cats there are three forms with very different causes: primary, nutritional secondary and renal secondary. The NAVLE tends to test whether you can tell them apart from the calcium, phosphorus and PTH pattern and the signalment.

Key facts

Hyperparathyroidism at a glance
  • Species and system: cat, endocrine (calcium regulation).
  • Primary (PHPT): autonomous PTH secretion, usually from a single parathyroid adenoma, in middle-aged to older cats.
  • Nutritional secondary (NSHP): growing kitten fed a calcium-poor, phosphorus-rich diet such as all meat.
  • Renal secondary (RSHP): develops with chronic kidney disease through phosphorus retention and low calcitriol; reported in up to 84% of cats with CKD.
  • Zoonotic or reportable: no.

What's inside

10 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Calcium and PTH physiology
  4. Primary hyperparathyroidism
  5. Nutritional secondary hyperparathyroidism
  6. Renal secondary hyperparathyroidism
  7. Don't confuse these hypercalcemia patterns
  8. Quick review
  9. Test yourself
  10. References
The full guide also has 5 tables, 3 self-test questions and 8 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Hyperparathyroidism on the NavleExam blog.

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