Members' NAVLE study guide

Feline Paw Pad Disease and Pillow Foot | NAVLE Guide

1,669 words 7 min read Reviewed November 14, 2026

Cats rarely show pad disease, but the ones that do are favourite exam cases. Lesions come from immune-mediated disease, allergy, tumours or organ disease elsewhere in the body, or trauma. Number of feet, pad texture and signalment sort most of them.

Key facts

Disease of pads at a glance
  • Species and system: cat, integumentary (pads and digits).
  • Plasma cell pododermatitis (pillow foot): soft, spongy swelling of the central pads on several feet, often with white striae; immune-mediated; test for FIV and FeLV; doxycycline first.
  • Pemphigus foliaceus: symmetric crusting of the face, pinnae and feet with caseous claw-fold material; prednisolone.
  • Eosinophilic lesions: a reaction pattern; look for flea, environmental or food allergy.
  • Footpad crusting with internal disease: pancreatic or bile duct carcinoma, hepatic disease (MSD).
  • Swollen toe, not pad, in an older cat: lung-digit syndrome; chest films first.

What's inside

13 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Pad anatomy
  4. Plasma cell pododermatitis
  5. Pemphigus foliaceus
  6. Eosinophilic granuloma and allergy
  7. Pad signs of internal disease
  8. Lung-digit syndrome: a digit, not a pad
  9. Differential diagnoses
  10. Prognosis
  11. Quick review
  12. Test yourself
  13. References
The full guide also has 3 tables, 3 self-test questions and 12 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Disease of pads on the NavleExam blog.

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Feline · Integumentary