Members' NAVLE study guide

Feline Anal Sac Disease

1,599 words 7 min read Reviewed November 13, 2026

The anal sacs are a pair of small scent glands beside the anus. In cats they cause trouble far less often than in dogs, but when they do, impaction is the usual problem and a hard, painless anal sac mass in an older cat should make you think of cancer.

Key facts

Anal sac disease at a glance
  • Species and system: cat; the anal sacs open beside the anus (integumentary on the NAVLE blueprint).
  • Frequency: common in dogs, infrequent in cats (MSD). A questionnaire study of veterinarians estimated non-neoplastic disease at 0.4% of cats and 15.7% of dogs (Corbee 2022).
  • Most common form in cats: impaction (MSD).
  • Classic presentation: scooting, licking or biting at the anus, painful defecation and straining.
  • Treatment cornerstone: manual expression and flushing; antibiotics or surgery for infection or recurrence.
  • Zoonotic: no.

What's inside

14 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Anal sac adenocarcinoma
  9. Prevention, control and public health
  10. Client communication
  11. Prognosis
  12. Quick review
  13. Test yourself
  14. References
The full guide also has 4 tables, 3 self-test questions and 4 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Anal sac disease on the NavleExam blog.

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Feline · Integumentary