Members' NAVLE study guide

Equine Gastric Ulcers: ESGD vs EGGD

1,675 words 7 min read 1 figure Reviewed November 12, 2026

Equine gastric ulcer syndrome (EGUS) is the umbrella term for erosions and ulcers of the terminal esophagus, the squamous (nonglandular) stomach, the glandular stomach and the proximal duodenum. Signs are vague, so diagnosis rests on gastroscopy, and the NAVLE expects you to separate squamous disease from glandular disease because their causes and treatment responses differ.

Key facts

Gastric ulceration at a glance
  • Species and system: horse (adults and foals); stomach and proximal duodenum.
  • Two diseases: equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD), named in the ECEIM consensus (Sykes et al., 2015).
  • Classic presentation: poor appetite, weight loss or poor body condition, mild colic and poor performance in a horse in training. Signs are nonspecific.
  • Definitive test: gastroscopy of an empty stomach with a 3 m endoscope.
  • Cornerstone treatment: omeprazole 4 mg/kg PO once daily for 28 days (label).
  • Not zoonotic or reportable.

What's inside

13 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Working through a case
  9. Prevention, control and public health
  10. Prognosis
  11. Quick review
  12. Test yourself
  13. References
The full guide also has 5 tables, 1 figure, 3 self-test questions and 6 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Gastric ulceration on the NavleExam blog.

More guides

Equine · Gastrointestinal/Digestive