Members' NAVLE study guide

Equine Chronic Diarrhea and Granulomatous Enteritis | NAVLE

1,594 words 7 min read 1 figure Reviewed November 12, 2026

Chronic diarrhea in the adult horse is diarrhea lasting more than a month, and it is usually a diagnostic puzzle rather than an emergency. The causes are mostly infiltrative, inflammatory or neoplastic, or a disturbance of colonic fermentation, not the infectious agents behind acute colitis. Granulomatous enteritis (GE) is one of the idiopathic inflammatory bowel diseases (IBD) of horses, and the NAVLE tends to present it as weight loss with low serum protein rather than as a diarrhea case.

Key facts

Chronic diarrhea-Granulomatous enteritis at a glance
  • Species and system: horse; small and large intestine.
  • Definition: diarrhea persisting longer than 1 month (MSD).
  • IBD group: granulomatous enteritis (GE), lymphocytic-plasmacytic enterocolitis (LPE), multisystemic eosinophilic epitheliotropic disease (MEED) and idiopathic focal eosinophilic enterocolitis (IFEE).
  • Classic presentation: weight loss, hypoproteinemia (protein-losing enteropathy and malabsorption), with or without diarrhea.
  • Predisposition: Standardbreds seem predisposed to GE and MEED, suggesting a genetic component (MSD).
  • Prognosis: grave for most forms; IFEE is the exception because a focal lesion can be resected.

What's inside

11 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prognosis
  9. Quick review
  10. Test yourself
  11. References
The full guide also has 4 tables, 1 figure, 3 self-test questions and 4 references, available to NAVLE members.

Read the full study guide

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Read the free overview article A shorter, free article on Chronic diarrhea-Granulomatous enteritis on the NavleExam blog.

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Equine · Gastrointestinal/Digestive