NAVLE Respiratory

Porcine Reproductive and Respiratory Syndrome – NAVLE Study Guide

Porcine Reproductive and Respiratory Syndrome (PRRS) is one of the most economically devastating viral diseases affecting the global swine industry, costing the United States swine industry approximately $664 million annually.

Overview and Clinical Importance

Porcine Reproductive and Respiratory Syndrome (PRRS) is one of the most economically devastating viral diseases affecting the global swine industry, costing the United States swine industry approximately $664 million annually. First recognized in the USA in 1987, PRRS has become endemic in most swine-producing countries worldwide.

The disease is characterized by two distinct clinical presentations: reproductive failure in breeding animals (late-term abortions, stillbirths, mummified fetuses, weak-born piglets) and respiratory disease in pigs of all ages, particularly young growing pigs.

High-YieldPRRS was originally called 'Mystery Swine Disease' and 'Blue Ear Disease' due to the characteristic cyanosis of the ears seen in some affected pigs. Remember: PRRS = Reproductive failure + Respiratory disease.
Species Geographic Origin Prototype Strain
PRRSV-1 (Betaarterivirus suid-1) European origin, now global Lelystad virus (LV)
PRRSV-2 (Betaarterivirus suid-2) North American origin, now global VR-2332

Etiology

PRRS is caused by Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), a small, enveloped, positive-sense single-stranded RNA virus classified in the family Arteriviridae, genus Betaarterivirus.

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