Porcine Mycoplasma hyopneumoniae Infection – NAVLE Study Guide
Overview and Clinical Importance
Mycoplasma hyopneumoniae (M. hyopneumoniae) is the primary etiological agent of enzootic pneumonia (EP), the most economically significant bacterial respiratory disease in swine worldwide. This organism is also a key contributor to the Porcine Respiratory Disease Complex (PRDC), where it acts as a primary pathogen that predisposes pigs to secondary infections with other viral and bacterial agents.
The disease causes substantial economic losses through reduced average daily gain (ADG), poor feed conversion efficiency, increased mortality, and costs associated with treatment, vaccination, and control measures. Prevalence of M. hyopneumoniae-compatible lung lesions at slaughter ranges from 30% to 80% depending on geographic region and management practices.
Etiology
M. hyopneumoniae belongs to the class Mollicutes and represents one of the smallest self-replicating organisms known. Key characteristics include:
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