NAVLE Gastrointestinal and Digestive

Ovine and Caprine Contagious Ecthyma – NAVLE Study Guide

Contagious ecthyma (also known as orf, sore mouth, scabby mouth, or contagious pustular dermatitis) is a highly contagious, zoonotic viral skin disease caused by the Orf virus (ORFV), a member of the genus Parapoxvirus in the family Poxviridae.

Overview and Clinical Importance

Contagious ecthyma (also known as orf, sore mouth, scabby mouth, or contagious pustular dermatitis) is a highly contagious, zoonotic viral skin disease caused by the Orf virus (ORFV), a member of the genus Parapoxvirus in the family Poxviridae. This disease has worldwide distribution and primarily affects sheep and goats, with goats typically experiencing more severe disease than sheep. It is one of the most common skin diseases in small ruminants and represents an important topic on the NAVLE due to its zoonotic potential and need for differentiation from foreign animal diseases.

The disease is characterized by proliferative skin lesions at mucocutaneous junctions, most commonly affecting the lips and muzzle. While typically self-limiting with low mortality in uncomplicated cases, secondary bacterial infections can significantly increase morbidity and mortality, especially in young lambs and kids.

High-YieldContagious ecthyma is a ZOONOTIC disease. Always wear gloves when handling affected animals. The virus can survive in dried scabs in the environment for months to years, making eradication difficult once established on a premise.
Feature Description
Family Poxviridae
Genus Parapoxvirus
Genome Linear double-stranded DNA, 130-150 kbp
GC Content Unusually high (~64%)
Morphology Oval/ovoid shape, 140 x 250 nm, characteristic criss-cross filament pattern
Environmental Stability Extremely resistant; survives months to years in dried scabs
Replication Site Cytoplasm of epithelial cells (keratinocytes)

Etiology

Causative Agent

The causative agent is the Orf virus (ORFV), which is the prototype species of the genus Parapoxvirus. Key characteristics include:

You've been studying hard

Create a free account to keep reading

Free accounts get 5 articles/day + daily practice question

Join vet students already studying with NavleExam.

No credit card needed — free account takes 30 seconds.

Create Free Account — Keep Reading Already have an account? Log in
or skip signup — just get daily questions

No spam. One question per day. Unsubscribe anytime.

Free NAVLE exam50 questions

Take the free NAVLE practice exam

50 exam-style questions across the NAVLE species. See your score as soon as you finish, then get the full answer key with explanations by email. No payment, no account.

Start the free exam →

NAVLE Exam Prep Platform

Everything you need to pass the NAVLE

✓
8,100+ Practice Questions
Exam-style with full explanations
✓
NAVLE Mock Exams
Exam-style, with full explanations
✓
Flashcard Mode
Species & topic quick review
✓
High Yield Question Packs
Blueprint-weighted, most-tested topics
Start free trial → See Plans & Pricing No credit card required to start