Ovine and Caprine Caseous Lymphadenitis – NAVLE Study Guide
Overview and Clinical Importance
Caseous Lymphadenitis (CLA), also known as cheesy gland or pseudotuberculosis, is a chronic, contagious bacterial disease affecting sheep and goats worldwide. CLA is caused by Corynebacterium pseudotuberculosis and is characterized by abscess formation in peripheral lymph nodes (external form) and internal organs (visceral form).
CLA represents a significant economic burden to the small ruminant industry due to carcass condemnation, hide and wool damage, decreased production, reproductive losses, and premature culling. Prevalence in endemic flocks can reach 30-50%, with morbidity increasing with age. The disease has no cure and once established in a flock, eradication is extremely difficult.
Etiology
Causative Agent
Corynebacterium pseudotuberculosis is a Gram-positive, facultatively intracellular, pleomorphic rod-shaped bacterium. Key characteristics include:
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