Members' NAVLE study guide

Feline Osteomyelitis (Bone Infection)

1,636 words 7 min read 1 figure Reviewed November 15, 2026

Osteomyelitis is infection and inflammation of the medullary cavity, cortex and periosteum of bone. It is uncommon in cats, but it matters because a swelling or draining tract over a bone can be bone infection, a tumor, or both, and the treatment is long and often surgical.

Key facts

Osteomyelitis at a glance
  • Species and system: cats; musculoskeletal.
  • Cause: mostly bacteria (Staphylococcus spp make up about 50% of cases in cats and dogs, MSD); fungi in endemic areas. Routes are hematogenous spread, direct trauma and surgery.
  • Classic presentation: lameness, pain and swelling over a bone, sometimes fever or a draining tract.
  • Key test: radiographs, then deep sampling (fine-needle aspirate or biopsy) for culture and cytology.
  • Treatment: culture-guided antibiotics plus debridement, sequestrum and implant removal when present.
  • Zoonotic or reportable: no, but some fungal causes are of public health concern.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Putting it together: a case approach
  5. Clinical signs
  6. Diagnosis
  7. Differential diagnoses
  8. Treatment and management
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 5 tables, 1 figure, 3 self-test questions and 5 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Osteomyelitis on the NavleExam blog.

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