Members' NAVLE study guide

Feline Lower Urinary Tract Disease (FLUTD)

1,473 words 7 min read Reviewed November 15, 2026

Feline lower urinary tract disease (FLUTD) is not a diagnosis. It is a syndrome of lower urinary tract signs in cats, caused by several different problems that look alike. The first job is to decide whether the cat is obstructed; the second is to find which cause is behind the signs.

Key facts

Feline lower urinary tract disease (flutd) at a glance
  • Species and system: cat, lower urinary tract (bladder and urethra).
  • Defining signs: hematuria, pollakiuria, stranguria and periuria (urinating outside the litter box).
  • Most common cause: feline idiopathic cystitis, a diagnosis of exclusion that accounts for around 55 to 65% of cases in published studies.
  • Other causes: urolithiasis (10 to 23% of cases), urethral plugs, bacterial urinary tract infection (uncommon in otherwise healthy adult cats), neoplasia, strictures and other anatomical or behavioural causes.
  • Emergency form: urethral obstruction, almost always in male cats.
  • Zoonotic or reportable: no.

What's inside

11 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention and prognosis
  9. Quick review
  10. Test yourself
  11. References
The full guide also has 4 tables, 3 self-test questions and 5 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Feline lower urinary tract disease (flutd) on the NavleExam blog.

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