Members' NAVLE study guide

Feline Heartworm Disease and HARD

1,524 words 7 min read 1 figure Reviewed November 14, 2026

Feline heartworm disease is caused by Dirofilaria immitis, transmitted by mosquitoes. Cats are not the natural host: infections are low in number, adult worms are short-lived and much of the harm comes from the lungs. A cat can be seriously sick or die suddenly, and no drug is available that safely kills the adult worms, so prevention is the real protection.

Key facts

Heartworm at a glance
  • Species and system: cat; respiratory and cardiovascular (mainly pulmonary arteries and lungs).
  • Cause: Dirofilaria immitis, spread by infected mosquitoes. Indoor cats can be infected.
  • Typical burden: often only 1 to 3 worms; microfilariae are usually absent.
  • Key syndrome: heartworm-associated respiratory disease (HARD), which often looks like feline asthma.
  • Treatment: no adulticide; supportive care and prevention.
  • Zoonotic: infected mosquitoes can transmit to people, but larvae die in the lungs and do not become patent (MSD).

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention, control and public health
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 4 tables, 1 figure, 3 self-test questions and 6 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Heartworm on the NavleExam blog.

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