Members' NAVLE study guide

Canine Seizures and Epilepsy

3,032 words 13 min read 2 figures Reviewed November 11, 2026

A seizure is a brief episode caused by excessive, synchronized activity of cerebral neurons; epilepsy is a brain disease that produces recurrent unprovoked seizures. Seizures are among the commonest neurological emergencies in dogs, and canine epilepsy affects about 0.5–0.8% of dogs seen in primary care (Merck). The exam expects you to sort a seizuring dog into the right cause category, choose the right first drug and act fast when a seizure will not stop.

Key facts

Seizure disorder at a glance
  • Species: Dog
  • System: Nervous (forebrain)
  • Cause categories: idiopathic epilepsy (genetic or presumed genetic), structural epilepsy (identifiable brain disease) and reactive seizures (normal brain, metabolic or toxic insult)
  • Classic presentation: a young adult dog with recurrent generalized tonic-clonic seizures and a normal examination between them
  • Emergency: status epilepticus, a seizure lasting more than 5 minutes; mortality in animals 25–39%
  • First-line maintenance drug: phenobarbital (target 15–35 µg/mL); bromide, levetiracetam, zonisamide as alternatives or add-ons

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention, control and client education
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 7 tables, 2 figures, 3 self-test questions and 11 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Seizure disorder on the NavleExam blog.

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Canine · Nervous