Members' NAVLE study guide

Canine Meningitis: SRMA, Bacterial and MUO

2,879 words 12 min read 2 figures Reviewed November 10, 2026

Meningitis is inflammation of the meninges. In dogs it often extends into the brain or spinal cord (meningoencephalitis, meningomyelitis). Most cases are immune-mediated rather than infectious, and the three diagnoses that matter most are steroid-responsive meningitis-arteritis (SRMA), bacterial meningitis and meningoencephalitis of unknown origin (MUO). Signalment, the neurological examination and the CSF usually separate them.

Key facts

Meningitis at a glance
  • Species and system: dog; nervous system (meninges, brain, spinal cord).
  • Causes: immune-mediated disease accounts for about 80-90% of inflammatory CNS disease in dogs and infection for 10-20% (Merck). In 1,140 dogs from two English referral centres, MUO made up 47.5% and SRMA 30.7% (Gonçalves 2021).
  • Classic SRMA: a dog under 2 years with fever, severe neck pain and a normal neurological examination, with marked non-degenerate neutrophilic pleocytosis in the CSF.
  • Classic bacterial meningitis: an adult dog with otitis media/interna, neurological deficits (often vestibular), and degenerate neutrophils with intracellular bacteria in the CSF.
  • Zoonotic or reportable: rabies must be considered in any dog with unexplained neurological signs. See the rabies guide. SRMA and MUO are not infectious.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention, control and public health
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 4 tables, 2 figures, 3 self-test questions and 12 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Meningitis on the NavleExam blog.

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Canine · Nervous