NAVLE Nervous

Canine Meningitis Study Guide

Meningitis refers to inflammation of the meninges, the protective membranes covering the brain and spinal cord. In dogs, meningitis represents an important category of neurological disease frequently tested on the NAVLE.

Overview and Clinical Importance

Meningitis refers to inflammation of the meninges, the protective membranes covering the brain and spinal cord. In dogs, meningitis represents an important category of neurological disease frequently tested on the NAVLE. Understanding the classification, clinical presentation, and management of different meningitis types is essential for veterinary practice.

Meningitis in dogs can be broadly categorized into infectious and non-infectious (immune-mediated) causes. Critically, non-infectious causes comprise approximately 80% of meningitis cases in dogs in Europe and the USA, with steroid-responsive meningitis-arteritis (SRMA) being the most common type overall.

Infectious Causes Non-Infectious (Immune-Mediated) Causes
Bacterial: Staphylococcus spp., Pasteurella spp., Streptococcus spp. Viral: Canine distemper virus, Rabies virus Fungal: Cryptococcus, Blastomyces, Histoplasma, Coccidioides Protozoal: Toxoplasma gondii, Neospora caninum Rickettsial: Rickettsia rickettsii (RMSF), Ehrlichia canis Steroid-Responsive Meningitis-Arteritis (SRMA) Most common cause of meningitis in dogs Meningoencephalitis of Unknown Origin (MUO): - Granulomatous meningoencephalomyelitis (GME) - Necrotizing meningoencephalitis (NME) - Necrotizing leukoencephalitis (NLE) Eosinophilic meningoencephalitis

Classification of Canine Meningitis

Acute Form (Most Common) Chronic Form
Severe cervical hyperesthesia (neck pain) Hunched posture, low head carriage Kyphosis (arched back) Pyrexia (fever greater than 39.2C) Stiff gait, reluctance to move Lethargy, inappetence Normal neurological exam Waxing and waning pain episodes May develop neurological deficits Paresis, ataxia possible Results from inadequate treatment or repeated relapses More difficult to manage Worse prognosis than acute form

Steroid-Responsive Meningitis-Arteritis (SRMA)

SRMA is the most common cause of meningitis in dogs. It is an immune-mediated inflammatory disease affecting the leptomeninges and associated arteries, characterized by marked neutrophilic pleocytosis in the CSF and excellent response to corticosteroid therapy.

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