NAVLE Gastrointestinal and Digestive

Porcine Gastric Ulcers Study Guide

Gastric ulceration in swine, more accurately termed gastroesophageal ulceration, is one of the most economically significant non-infectious diseases in modern swine production.

Overview and Clinical Importance

Gastric ulceration in swine, more accurately termed gastroesophageal ulceration, is one of the most economically significant non-infectious diseases in modern swine production. Lesions are almost exclusively confined to the pars esophagea, the nonglandular region of the stomach surrounding the esophageal opening. This condition represents a significant cause of sudden death in grower-finisher pigs and is a common finding at slaughter.

Surveys from abattoirs reveal that approximately 80-90% of pigs have some type of lesion in the pars esophageal region at slaughter, with 20% showing erosive lesions and an additional 60% demonstrating pre-ulcerative parakeratosis lesions.

High-YieldOn the NAVLE, gastric ulcers in pigs are strongly associated with finely ground feed (less than 700 microns particle size), sudden death with pale carcass, and melena WITHOUT diarrhea. The absence of diarrhea is a key differentiating feature from other causes of GI hemorrhage.
Region Epithelium Type Clinical Significance
Pars Esophagea Stratified squamous (non-glandular) NO mucus protection; site of ulceration
Cardiac Region Glandular mucosa Mucus-producing; protected
Fundic Region Glandular (parietal and chief cells) Produces HCl and pepsinogen
Pyloric Region Glandular mucosa Mucus and gastrin secretion

Anatomy and Pathophysiology

Gastric Anatomy

The porcine stomach has four distinct anatomical regions with different mucosal characteristics:

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