NAVLE Respiratory

Ovine and Caprine Pneumonia Study Guide

Pneumonic pasteurellosis is a severe, economically devastating respiratory disease affecting sheep and goats worldwide.

Overview and Clinical Importance

Pneumonic pasteurellosis is a severe, economically devastating respiratory disease affecting sheep and goats worldwide. It represents the most common bacterial cause of respiratory disease in small ruminants and is a frequent topic on the NAVLE examination.

The disease is caused primarily by Mannheimia haemolytica (formerly Pasteurella haemolytica biotype A), Pasteurella multocida, and Bibersteinia trehalosi (formerly Pasteurella trehalosi). These organisms are normal commensals of the upper respiratory tract that become pathogenic under specific predisposing conditions.

High-YieldM. haemolytica serotype A2 is the predominant strain in sheep and goats (unlike A1 in cattle). This is important for understanding why bovine vaccines are not effective in small ruminants.
Organism Common Serotype Disease Form Key Features
Mannheimia haemolytica A2 (sheep and goats); A6, A9 also reported Pneumonia and septicemia in young lambs; pneumonia in weaned animals Most common isolate; produces leukotoxin; fibrinous bronchopneumonia
Pasteurella multocida Serogroup A most common Bronchopneumonia; septic arthritis outbreaks Less common; suppurative pneumonia; less fibrin deposition
Bibersteinia trehalosi T3, T4, T10, T15 Septicemia in weaned lambs (4-9 months); pneumonia less common Highest case fatality rate; systemic pasteurellosis; GI portal of entry

Etiology

Pneumonic pasteurellosis in sheep and goats is caused by members of the family Pasteurellaceae, which are Gram-negative, beta-hemolytic, aerobic, non-motile, non-spore-forming coccobacilli.

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