Members' NAVLE study guide

Feline Hemangiosarcoma

1,395 words 7 min read Reviewed November 14, 2026

Hemangiosarcoma (HSA) is a malignant tumour of vascular endothelial cells. In cats it appears as a skin or subcutaneous mass or as a tumour in an abdominal organ, and it matters on the NAVLE because the visceral form ruptures and presents as collapse with a hemoabdomen. (The benign counterpart, hemangioma, is a well-circumscribed vascular mass that is cured by excision; the two are told apart on histopathology.)

Key facts

Hemangioma at a glance
  • Species and system: cat; hemic/lymphatic (vascular endothelium).
  • Cause: unknown for visceral disease; ultraviolet exposure is linked to skin forms, especially in white-coated cats (MSD).
  • Classic presentation: a red-purple skin mass on a sparsely haired, pale area, or collapse with pale gums, anaemia and abdominal effusion.
  • Signalment: older cats; the MSD Manual notes that angiosarcomas seem to occur most often in older neutered males.
  • Behaviour: locally invasive and likely to metastasise; the MSD Manual calls it the soft-tissue tumour most likely to grow fast and spread.
  • Zoonotic or reportable: no.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention, control and public health
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 4 tables, 3 self-test questions and 7 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Hemangioma on the NavleExam blog.

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Feline · Hemic/Lymphatic