Members' NAVLE study guide

Feline Cardiomyopathy (HCM, RCM, DCM)

2,814 words 12 min read 2 figures Reviewed November 13, 2026

Cardiomyopathies are diseases of the heart muscle itself, and they are the most common heart diseases of adult cats. Hypertrophic cardiomyopathy (HCM) alone affects roughly 15% of the general cat population, mostly as silent disease, but a minority of cats develop congestive heart failure (CHF), arterial thromboembolism (ATE) or sudden death.

Key facts

Cardiomyopathy at a glance
  • Species and system: cat; cardiovascular.
  • Phenotypes: HCM (most common, about 60% of referred cases), restrictive (RCM), dilated (DCM, now under 5%), arrhythmogenic right ventricular (ARVC) and nonspecific phenotype.
  • Genetics: MYBPC3 mutations in Maine Coon (A31P) and Ragdoll (R820W) cats; most affected cats are nonpedigree.
  • Classic presentation: older male cat with sudden tachypnea and dyspnea, or acute painful hindlimb paralysis; many cats are subclinical with a murmur or gallop.
  • Key prognostic marker: left atrial (LA) size.
  • Not zoonotic, not reportable.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention and control
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 5 tables, 2 figures, 3 self-test questions and 9 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Cardiomyopathy on the NavleExam blog.

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Feline · Cardiovascular