Members' NAVLE study guide

Equine Valvular Disease and Murmurs | NAVLE Guide

1,576 words 8 min read Reviewed November 12, 2026

Acquired valvular disease is a common reason for a murmur in a horse. Nearly all of it is regurgitant rather than stenotic, and many horses live with it for years. The exam skill is to match a murmur to a valve by timing and location, and to know which findings change the outlook.

Key facts

Valvular disease at a glance
  • Species and system: horse; cardiovascular.
  • Most affected valves: mitral, aortic and tricuspid; the mitral valve is most commonly involved (MSD).
  • Aortic regurgitation: a diastolic murmur, most often in older horses, from calcification or degeneration of the valve (MSD).
  • Presentation: frequently an incidental murmur. Signs usually appear only with heart failure.
  • Infective endocarditis: usually aortic or mitral; fever plus a murmur is the clue.
  • Zoonotic: no.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Putting it together in practice
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 4 tables, 3 self-test questions and 8 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Valvular disease on the NavleExam blog.

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Equine · Cardiovascular