Members' NAVLE study guide

Osteomyelitis in Dogs

2,850 words 12 min read 3 figures Reviewed November 10, 2026

Osteomyelitis is inflammation of the medullary cavity, cortex and periosteum of bone, nearly always because of infection. In dogs it is usually bacterial and usually follows an open fracture, a bite or orthopedic surgery, especially when implants are present; blood-borne infection and fungal disease are less common. Once dead bone or a loose implant is colonized, antimicrobials alone rarely cure it, so the case is as much surgical as medical.

Key facts

Osteomyelitis at a glance
  • Species and system: dog (also cats); musculoskeletal.
  • Routes: direct trauma (open fractures, bites, gunshot), iatrogenic (after surgery) and hematogenous (rare in adult dogs; young or immunocompromised patients most at risk).
  • Cause: Staphylococcus spp. in about half of cases; also streptococci, E. coli, Proteus, Pasteurella, Pseudomonas, anaerobes, Brucella canis; regional fungi.
  • Classic presentation: lameness, pain, swelling and a draining tract weeks after fracture repair, with lysis, sequestra and loose implants on radiographs.
  • Diagnosis: radiographs, then culture of deep tissue, bone or implant (not a surface swab).
  • Treatment: culture-guided antimicrobials plus removal of dead bone and loose implants.
  • Zoonotic note: Brucella canis can infect people (CDC); the fungi are acquired from the environment, and Merck states that people do not catch blastomycosis from animals.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention, control and public health
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 6 tables, 3 figures, 3 self-test questions and 23 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Osteomyelitis on the NavleExam blog.

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