Members' NAVLE study guide

Canine Neonatal Care and Resuscitation

3,187 words 14 min read 2 figures Reviewed November 10, 2026

The neonatal period in puppies covers roughly the first three weeks of life, and it is when most pre-weaning deaths happen. Newborn puppies cannot control their body temperature, store little energy and have immature kidneys and immunity, so small problems such as chilling or a missed feed quickly become life-threatening. Good neonatal care means a well-managed birth, early colostrum, a warm environment, daily weighing and a fast, ordered response to a weak puppy.

Key facts

Neonatal care at a glance
  • Species and system: dogs (also cats); reproductive and neonatal medicine.
  • Mortality: reported neonatal mortality is 9 to 26% over the first 21 days, highest in the first week; a 2019 review puts the loss at about 10% of live-born puppies by 21 days.
  • Classic presentation: the weak, cold, crying puppy that will not nurse, with the neonatal triad of hypothermia, hypoglycemia and dehydration.
  • Immunity: puppies are born almost without IgG and depend on colostrum absorbed in the first 12 to 16 hours.
  • Infectious causes: bacterial sepsis and canine herpesvirus-1 (CHV-1) are the classic causes of "fading" puppies.
  • Zoonotic or reportable: CHV-1 is neither. Toxocara canis, passed to puppies across the placenta and in milk, is zoonotic.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention, control and public health
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 7 tables, 2 figures, 3 self-test questions and 12 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Neonatal care on the NavleExam blog.

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Canine · Reproductive