Members' NAVLE study guide

Canine MRSA: Resistant Staph Infections

2,840 words 11 min read 2 figures Reviewed November 10, 2026

Methicillin-resistant Staphylococcus aureus (MRSA) is a human-adapted bacterium that dogs usually pick up from people. In dogs it causes the same skin, wound and ear infections as susceptible staphylococci, but beta-lactam antibiotics will not work and the choice of other drugs is narrow. It matters for the NAVLE because it combines three tested themes: antimicrobial resistance, antimicrobial stewardship and zoonotic risk in both directions.

Key facts

Methicillin-resistant Staphylococcus aureus (MRSA) at a glance
  • Species and system: dog (also cats, horses and people); mainly skin, surgical sites, wounds and ears.
  • Cause: S. aureus carrying the mecA gene, which makes it resistant to virtually all beta-lactams; usually multidrug-resistant as well.
  • Source: most MRSA in dogs comes from people; dog strains mirror the human strains of the same region.
  • Classic presentation: pyoderma or a surgical-site infection that fails to respond to a cephalosporin, in a dog with recent antimicrobials, hospital stays or a household member who works in health care.
  • Key tests: cytology to confirm infection, then culture with species identification and susceptibility.
  • Zoonotic: yes. Transmission is mostly human to dog, but dogs can pass MRSA back to people.

What's inside

12 sections in the full guide
  1. Key facts
  2. How the NAVLE tests this
  3. Cause and pathophysiology
  4. Clinical signs
  5. Diagnosis
  6. Differential diagnoses
  7. Treatment and management
  8. Prevention, control and public health
  9. Prognosis
  10. Quick review
  11. Test yourself
  12. References
The full guide also has 4 tables, 2 figures, 3 self-test questions and 10 references, available to NAVLE members.

Read the full study guide

The full guide is part of every NAVLE plan, with diagnosis and treatment tables, figures, a quick review and self-test questions. Start a free trial to try the question bank, or log in if you are already a member.

Read the free overview article A shorter, free article on Methicillin-resistant Staphylococcus aureus (MRSA) on the NavleExam blog.

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