Equine Rabies Suspect Study Guide
Overview and Clinical Importance
Rabies is a fatal, neurotropic viral disease caused by the rabies virus (RABV), a member of the genus Lyssavirus within the family Rhabdoviridae. This zoonotic disease affects all mammals and has the highest case fatality ratio of any infectious disease. Although equine rabies is relatively rare (accounting for less than 1% of all rabies cases in the United States), it represents a critical public health concern due to its invariable fatality and potential for human transmission.
The AAEP classifies rabies vaccination as a core vaccine for all equids. The hallmark challenge of equine rabies is its highly variable clinical presentation, with insidious onset being extremely common. Clinical signs can mimic numerous other neurologic conditions, making early recognition critical for both animal welfare and human safety.
Etiology
Viral Characteristics
The rabies virus is a bullet-shaped, enveloped, single-stranded, negative-sense RNA virus. The virion measures approximately 180 nm in length and 75 nm in diameter. The viral genome encodes five structural proteins:
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