NAVLE Integumentary

Canine Pyoderma Study Guide

Pyoderma (literally meaning "pus in the skin") is among the most common dermatologic conditions in dogs and represents one of the primary reasons for antimicrobial prescribing in small animal practice.
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Overview and Clinical Importance

Pyoderma (literally meaning "pus in the skin") is among the most common dermatologic conditions in dogs and represents one of the primary reasons for antimicrobial prescribing in small animal practice. Understanding pyoderma classification, diagnosis, and treatment is essential for NAVLE success and clinical practice.

The condition is almost always secondary to an underlying disease process, making identification and treatment of primary causes crucial for long-term management.

High-YieldStaphylococcus pseudintermedius is the causative agent in greater than 90% of canine pyoderma cases. This coagulase-positive bacterium produces beta-lactamase, so empirical use of penicillin, amoxicillin, or ampicillin alone should be avoided.
Organism Frequency Clinical Significance
S. pseudintermedius Greater than 90% Primary pathogen; coagulase-positive; produces beta-lactamase; can be methicillin-resistant (MRSP)
S. schleiferi 5-10% Common in chronic recurrent pyoderma; often resistant to cephalosporins
S. aureus 4-8% Human pathogen; zoonotic potential; dogs may acquire from human contact
Pseudomonas aeruginosa 4-5% Deep pyoderma; post-grooming furunculosis; requires fluoroquinolones
E. coli, Proteus spp. 3-5% Secondary invaders in deep pyoderma; indicate need for culture

Etiology and Pathophysiology

Causative Organisms

Staphylococcus pseudintermedius is the predominant pathogen in canine pyoderma, isolated in greater than 90% of cases. This organism is part of the normal canine mucosal flora, colonizing the nares, perineum, and oral mucosa.

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