NAVLE Nervous

Canine Intervertebral Disc Disease Study Guide

Intervertebral disc disease (IVDD) is the most common cause of spinal cord injury in dogs and represents a significant category of neurological disease on the NAVLE examination.

Overview and Clinical Importance

Intervertebral disc disease (IVDD) is the most common cause of spinal cord injury in dogs and represents a significant category of neurological disease on the NAVLE examination. This condition occurs when the intervertebral disc degenerates and herniates, causing compression and/or contusion of the spinal cord. Understanding the pathophysiology, clinical presentation, diagnostic approach, and treatment options is essential for successful case management.

The intervertebral disc consists of two main components: the nucleus pulposus (a gelatinous center rich in proteoglycans and water) and the annulus fibrosus (a concentric ring of fibrous lamellae composed primarily of collagen). Disc degeneration leads to loss of shock-absorbing capacity and can result in herniation and spinal cord compression.

Feature Type I Type II Type III/ANNPE
Degeneration Chondroid metaplasia Fibroid metaplasia Normal/minimal
Herniation Extrusion (nucleus through annulus) Protrusion (annulus bulges) Extrusion (high velocity)
Onset Acute (hours) Chronic (weeks-months) Peracute (seconds-minutes)
Age 2-6 years 5+ years Any age
Breeds Chondrodystrophic (Dachshund, Beagle) Large breeds (GSD, Doberman) Medium-large breeds
Compression Contusion + Compression Primarily Compression Primarily Contusion
Calcification Common Rare Absent

Pathophysiology and Classification

Hansen Classification System

The Hansen classification system, developed in the 1950s, remains the foundation for understanding IVDD pathology. The system is based on the type of disc degeneration and the nature of disc herniation.

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