NAVLE Respiratory

Bovine Contagious Pleuropneumonia Study Guide

Contagious Bovine Pleuropneumonia (CBPP) is a severe infectious respiratory disease of cattle caused by Mycoplasma mycoides subspecies mycoides small colony type.

Overview and Clinical Importance

Contagious Bovine Pleuropneumonia (CBPP) is a severe infectious respiratory disease of cattle caused by Mycoplasma mycoides subspecies mycoides small colony type. It is classified as a World Organization for Animal Health (WOAH) notifiable disease and represents one of the most economically devastating cattle diseases in endemic regions.

CBPP is characterized by severe fibrinous pleuropneumonia, distinctive "marbled lung" appearance, and the formation of pulmonary sequestra in chronic cases. The disease continues to cause significant economic losses across sub-Saharan Africa, where it remains endemic.

Status Regions/Countries Year of Eradication/Last Case
Endemic Sub-Saharan Africa (24 countries), Parts of Asia Ongoing transmission
Eradicated USA, Canada, UK, Australia, Most of Europe USA (1892), UK (1898), Australia (1973)
Recent Control Portugal, Spain, Italy, China Portugal (1999), China (1996)

Etiology and Pathogenesis

Causative Agent

Mycoplasma mycoides subsp. mycoides small colony type (MmmSC) is the etiological agent of CBPP. This organism belongs to the class Mollicutes and is characterized by:

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