NAVLE Reproductive

Canine Pyometra and Metritis Study Guide

Pyometra and metritis are critical uterine infections in intact female dogs that represent veterinary emergencies requiring prompt recognition and treatment.

Overview and Clinical Importance

Pyometra and metritis are critical uterine infections in intact female dogs that represent veterinary emergencies requiring prompt recognition and treatment. Pyometra is defined as the accumulation of purulent material within the uterine lumen, typically occurring during or after diestrus in non-pregnant bitches. Metritis is acute inflammation and infection of the uterus occurring in the immediate postpartum period, usually within 1-2 weeks after whelping.

Both conditions can progress to life-threatening sepsis and multi-organ dysfunction if left untreated. Pyometra affects up to 25% of intact female dogs by 10 years of age, making it one of the most common reproductive disorders encountered in small animal practice and a high-yield topic for the NAVLE examination.

Parameter Clinical Significance
Prevalence 23-25% of intact bitches develop pyometra by 10 years of age
Mean Age at Diagnosis 7-9 years (range: 3 months to 20 years)
Timing Post-Estrus Typically 1-3 months after estrus (during diestrus/metestrus)
Nulliparous Risk Nulliparous bitches are 6x more likely to develop pyometra
Mortality Rate 3-10% with appropriate treatment; higher if untreated or with sepsis
Higher Risk Breeds Reported Frequency
Bernese Mountain Dog Significantly increased risk
Rottweiler Increased risk
Cavalier King Charles Spaniel Increased risk
Golden Retriever Increased risk (ABCC4 gene association)
Labrador Retriever 8-38% of pyometra cases

Pyometra

Definition and Epidemiology

Pyometra (literally meaning "pus in the uterus") is an infectious and inflammatory disorder of the uterus characterized by bacterial infection and accumulation of purulent exudate in the uterine lumen. It is the most prevalent reproductive disease in intact female dogs.

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