NAVLE Infectious Disease

Canine CIRDC (Kennel Cough): NAVLE Study Guide

CIRDC is the most common canine respiratory infectious syndrome. The NAVLE tests pathogen identification, treatment decisions, and when to worry about Canine Influenza vs. Bordetella.

CIRDC comes up on the NAVLE in a few different flavors: the classic post-kennel coughing dog that needs no treatment, the pneumonia complication that does, and the CIV outbreak question that tests whether you know your H3N8 from your H3N2. The pathogen list is long, but the exam almost always anchors on Bordetella and CIV. Know those two cold and the rest falls into place.

The Pathogens: What Each One Actually Does

CIRDC is a syndrome, not a single infection. Multiple pathogens cooperate – viral agents damage the mucociliary apparatus and the epithelial barrier, then Bordetella and Mycoplasma colonize the compromised mucosa. This is why simple cases escalate to pneumonia when the dog’s immune defenses are already stretched by shelter stress, crowding, and suboptimal nutrition.

Pathogen Type Key Feature NAVLE Relevance
Bordetella bronchiseptica Gram– coccobacillus Adheres to ciliated epithelium; produces BOR-1 β-lactamase Most important bacterial cause; first-line abx = doxycycline
Canine Parainfluenza Virus (CPiV) Paramyxovirus Epithelial damage; synergizes with Bordetella Included in DA2PP core vaccine
Canine Adenovirus Type 2 (CAV-2) Adenovirus Upper respiratory tropism; cross-protects against CAV-1 Core DA2PP vaccine antigen; NOT the hepatitis strain
Mycoplasma spp. Atypical bacteria No cell wall; common co-pathogen in pneumonia Covered by doxycycline; amoxicillin does NOT work
CIV H3N8 Influenza A Equine origin; emerged USA 2004 Shedding up to 7–10 days; isolation 7 days
CIV H3N2 Influenza A Avian origin; emerged USA 2015; more virulent Shedding up to 24 days; isolation 21 days; cats susceptible

Clinical Signs: What Looks Like What

The signature of uncomplicated CIRDC is that harsh, honking, dry cough – the kind that sounds like the dog has something stuck in its throat. Tracheal palpation reproduces it. The dog is typically bright, eating normally, and afebrile. That last point is the key examiner tell: no fever, no lethargy, no anorexia. The dog looks fine, it just coughs.

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