NAVLE Gastrointestinal and Digestive

Camelidae and Cervidae Necrotic Stomatitis Study Guide

Necrotic stomatitis (oral necrobacillosis) is a serious infectious disease affecting the oral cavity of camelids (llamas, alpacas) and cervids (deer, elk, reindeer).

Overview and Clinical Importance

Necrotic stomatitis (oral necrobacillosis) is a serious infectious disease affecting the oral cavity of camelids (llamas, alpacas) and cervids (deer, elk, reindeer). The condition is characterized by necrotizing, ulcerative lesions of the oral mucosa caused primarily by Fusobacterium necrophorum, a gram-negative, obligate anaerobic bacterium. This disease represents a significant cause of morbidity and mortality in both domestic and wild populations of these species.

In camelids, necrotic stomatitis is relatively uncommon but can occur as part of a broader syndrome called alimentary necrobacillosis, which may involve the esophagus and gastric compartments. In cervids, the disease is more commonly recognized as part of the lumpy jaw complex or can present as primary oral lesions, particularly in farmed deer populations where it represents one of the most economically important diseases.

High-YieldF. necrophorum is a normal inhabitant of the gastrointestinal tract and requires mucosal damage to establish infection. On the NAVLE, always consider predisposing factors such as coarse feed, dental eruption, trauma, stress, or concurrent disease when presented with oral necrotic lesions.
Subspecies Characteristics Clinical Relevance
subsp. necrophorum (Biotype A) More virulent; produces higher leukotoxin levels Primary cause of disease in animals; isolated more frequently from infections
subsp. funduliforme (Biotype B) Less virulent; lower leukotoxin production More commonly associated with human infections (Lemierre syndrome)

Etiology

Primary Causative Agent

Fusobacterium necrophorum is the primary etiologic agent of necrotic stomatitis. Key characteristics include:

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