NAVLE Multisystemic

Camelidae and Cervidae Foot and Mouth Disease Study Guide

Foot and Mouth Disease (FMD) is a highly contagious viral disease that affects cloven-hoofed animals, including members of the Camelidae (llamas, alpacas, dromedaries, and Bactrian camels) and Cervidae (deer species) families.

Overview and Clinical Importance

Foot and Mouth Disease (FMD) is a highly contagious viral disease that affects cloven-hoofed animals, including members of the Camelidae (llamas, alpacas, dromedaries, and Bactrian camels) and Cervidae (deer species) families. Understanding FMD susceptibility in these species is crucial for veterinarians, as these animals may serve as reservoir hosts or experience subclinical infections that can complicate disease control efforts.

FMD represents one of the most economically devastating transboundary animal diseases globally, with significant implications for international trade and livestock movement. While camelids and cervids generally show different susceptibility patterns compared to traditional livestock, their role in FMD epidemiology remains clinically relevant for the NAVLE examination.

Serotype Geographic Distribution Clinical Significance
O Most endemic regions (not southern Africa) Most common serotype in recent outbreaks
A Most endemic regions (not southern Africa) Second most prevalent globally
Asia 1 Asia only Regional importance in Asia
SAT 1, 2, 3 Africa (SAT 3 limited to southern Africa) African buffalo reservoir
C Not detected since 2004 Possibly extinct

Etiology and Pathophysiology

Causative Agent

Foot and Mouth Disease virus (FMDV) belongs to the genus Aphthovirus within the family Picornaviridae. The virus is a small (25-30 nm), non-enveloped, icosahedral capsid containing a positive-sense single-stranded RNA genome of approximately 8.3 kb.

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