NAVLE Multisystemic

Bovine Vesicular Stomatitis Study Guide

Vesicular stomatitis (VS) is a viral disease of livestock caused by vesicular stomatitis virus (VSV), a member of the Rhabdoviridae family.

Overview and Clinical Importance

Vesicular stomatitis (VS) is a viral disease of livestock caused by vesicular stomatitis virus (VSV), a member of the Rhabdoviridae family. It is found only in the Americas and produces vesicular lesions that are clinically indistinguishable from foot-and-mouth disease (FMD), making it a critical differential diagnosis on the NAVLE.

In cattle, VS causes significant economic losses through decreased milk production, weight loss, and secondary mastitis. The disease is reportable and requires immediate notification to state and federal animal health officials.

Serotype Geographic Range Clinical Significance
New Jersey (VSV-NJ) North America, Endemic in Mexico/Central America Most common serotype in U.S. outbreaks
Indiana (VSV-IND) South America (subtypes IND-1, IND-2, IND-3) Less common in cattle, rare in swine

Etiology

Viral Characteristics

Vesicular stomatitis virus (VSV) belongs to the genus Vesiculovirus within the family Rhabdoviridae. The virus is enveloped with a characteristic bullet-shaped virion containing single-stranded, negative-sense RNA.

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