NAVLE Reproductive

Bovine Uterine Prolapse Study Guide

Uterine prolapse (prolapsus uteri) is a sporadic but life-threatening postpartum emergency in cattle characterized by complete eversion of the uterus through the cervix and vagina, resulting in its protrusion outside the body.

Overview and Clinical Importance

Uterine prolapse (prolapsus uteri) is a sporadic but life-threatening postpartum emergency in cattle characterized by complete eversion of the uterus through the cervix and vagina, resulting in its protrusion outside the body. The condition occurs most commonly within hours of calving when the cervix is still dilated and the uterus lacks tone. Without prompt veterinary intervention, affected cows are at significant risk of hypovolemic shock, hemorrhage, and death. Uterine prolapse represents a true veterinary emergency with reported incidence rates of 0.002% to 1% of calvings, with higher prevalence in beef cattle (1%) compared to dairy cattle (0.6%).

Factor Category Specific Risk Factors and Mechanisms
Metabolic Hypocalcemia: Most significant risk factor; reduces myometrial contractility and tone. Serum calcium less than 8 mg/dL significantly associated with uterine prolapse. Multiparous dairy cows at highest risk. Hypomagnesemia: Contributes to uterine atony Negative energy balance: Compromises uterine involution
Obstetrical Dystocia: Leads to myometrial fatigue and trauma; 57.7% of prolapse cases required calving assistance Excessive traction: Manual extraction may initiate uterine eversion Retained fetal membranes: Continued straining to expel placenta Uterine overdistension: Twin pregnancy, hydrops
Environmental Positioning: Calving on sloped surface with hindquarters lower than forequarters Confinement: Lack of exercise during late gestation Prolonged recumbency: Gravitational effects on flaccid uterus
Patient Factors Parity: Risk increases with age (associated with decreased calcium mobilization) Prior vaginal prolapse: Increases risk of postpartum uterine prolapse Poor body condition: Nutritional deficiencies

Etiology and Pathophysiology

Uterine prolapse occurs when the uterus undergoes complete eversion through the open cervix immediately following or within several hours of parturition. The pathophysiology involves loss of myometrial tone combined with continued straining (tenesmus), which forces the flaccid uterus through the dilated cervix. Unlike vaginal prolapse which occurs prepartum, uterine prolapse is exclusively a postpartum condition.

Predisposing Factors

High-YieldHypocalcemia is the most common underlying cause of uterine prolapse in multiparous dairy cows. Calcium is essential for smooth muscle contraction, and hypocalcemia leads to uterine atony. Studies show cows with uterine prolapse have significantly lower serum calcium concentrations (mean 8.22 mg/dL) compared to control animals.
Assessment Area Clinical Findings
Prolapsed Organ Large mass hanging from vulva (often to hock level) Visible caruncles on endometrial surface (pathognomonic) Progressive edema, congestion, and discoloration Possible contamination with bedding, feces, debris Placenta may or may not be attached
Systemic Status Uncomplicated: Alert, ambulatory, normal vital signs With hypocalcemia: Weakness, depression, subnormal temperature, recumbency With shock: Tachycardia, extreme pallor, prostration, cold extremities
Complications Uterine artery rupture (internal hemorrhage) Bladder or intestinal entrapment within prolapse Severe lacerations or necrosis of uterine tissue Hypovolemic or septic shock

Clinical Presentation

Characteristic Findings

The clinical presentation of uterine prolapse is distinctive and unmistakable. The prolapsed uterus appears as a large, heavy mass of tissue protruding from the vulva, often hanging below the level of the hocks when the cow is standing. The exposed endometrial surface displays numerous caruncles (discrete, mushroom-shaped structures that served as maternal attachment sites for the placental cotyledons). The presence of caruncles definitively distinguishes uterine prolapse from vaginal prolapse.

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