NAVLE Special Senses

Bovine Skin Diseases Study Guide

This study guide covers two high-yield bovine skin conditions: Ocular Squamous Cell Carcinoma (OSCC) and Dermatophytosis (Ringworm).

Overview and Clinical Importance

This study guide covers two high-yield bovine skin conditions: Ocular Squamous Cell Carcinoma (OSCC) and Dermatophytosis (Ringworm). OSCC is the most common neoplasm in cattle, accounting for approximately 80% of tumors identified at slaughter, while dermatophytosis represents the most common fungal skin infection in cattle with significant zoonotic potential.

Risk Factor Clinical Significance
Breed Herefords most commonly affected; also Simmental, Holstein; breeds with white faces and lack of periocular pigmentation
Periocular Pigmentation Lack of pigmentation around eyes increases UV susceptibility; selecting for pigmented eyelids reduces incidence
UV Exposure Higher incidence at lower latitudes and higher altitudes; prolonged sunlight exposure critical factor
Age Generally develops in cattle greater than 5-7 years; rarely in cattle less than 3 years
Viral Factors Bovine papillomavirus suspected role; may induce precancerous papillomas
Location Frequency Clinical Features
Limbus ~75% Junction of cornea and sclera; medial or lateral canthus; most common site
Third Eyelid 38-70% Nictitating membrane; often surgical excision amenable
Eyelids 10-20% Upper and lower eyelid margins; may require enucleation if extensive

Section 1: Ocular Squamous Cell Carcinoma (Cancer Eye)

Definition and Epidemiology

Ocular squamous cell carcinoma (OSCC), commonly called "cancer eye," is a primary neoplasm of epithelial origin affecting the ocular and periocular structures of cattle. It represents the most economically significant tumor in the cattle industry, with losses estimated at approximately $20 million annually in the United States alone.

OSCC predominantly affects cattle over 5-7 years of age and rarely occurs in animals less than 3 years old. The prevalence varies geographically, being higher in southwestern regions and lower latitudes with greater UV exposure.

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